More information: Jiajia Ye et al, Nutrient deprivation induces mouse embryonic diapause mediated by Gator1 and Tsc2, Development (2024). DOI: 10.1242/dev.202091 ...

Mechanistically, the FGF21/βKlotho signaling pathway activated PPP6C phosphatase activity, which recruited and mediated the dephosphorylation of TSC2 at ... patients and mouse models of MASH ...