The part that activated microglia have in the pathogenesis of neuropathic pain is not well understood. The results of a recent study by Zhang et al. have now shown that both CNS-resident microglia ...

Microglia are specialized immune cells that ... an NSAID called Ketorolac used to treat mild-to-moderate pain, were diagnosed with Alzheimer's less than individuals who did not take the drug.

View Full Profile. Learn about our Editorial Policies. This lack of progress has prompted many research groups to look instead at non-neuronal cells in the brain, and in particular, at immune cells ...

They also found that microglia, which are resident immune cells in the brain, incorporate these micronuclei, thereby altering gene expression patterns and microglial characteristics. The brains of ...