to disease. Microglia, often referred to as the nervous system’s immune cells, monitor neuronal health. They are activated by neuronal injury or infection to produce pro-inflammatory factors (M1 ...

Pharmaceutical companies ramp up efforts to get the brain’s immune cells to help treat Alzheimer’s disease and other conditions ... progress has prompted many research groups to look instead at ...

While they act as first responders that protect neural health, some microglia exacerbate neurodegeneration and propel the progression of Alzheimer's disease. Understanding these differences has ...

This crew is called the microglia—the immune cells of the central nervous system. Microglia are imperative to maintaining neuronal function ... of neurodegenerative diseases like Alzheimer's ...

As aggregate accumulation is characteristic of many neurodegenerative diseases such as Alzheimer’s disease and Parkinson’s disease, and ultimately results in neuronal death, this suggests that ...

They are responsible for immune surveillance, mediating inflammation, supporting neuronal development, and participating in synaptic pruning. In addition, dysregulation of microglia is increasingly ...

These features make Ncyte® Microglia highly suitable for studying microglial behavior in disease-relevant contexts ... supporting neuronal development, and participating in synaptic pruning.

We use induced pluripotent stem cells (iPSCs) representing neurological and psychiatric diseases. Differentiation of iPSCs into neurons, astrocytes, microglia allow us to analyze aberrant gene ...