Cell division is essential to the propagation of life. During cell division, mitotic spindles segregate duplicated chromosomes with high fidelity. Spindle structure depends on the proper polar ...

The subsequent breakdown of the nuclear envelope terminates prophase and initiates prometaphase, during which the chromosomes become attached to and positioned on the mitotic spindle as it forms.

For almost a century, our understanding of the tiny structure at the centre of the cell called the centrosome was limited to its ability to organize mitotic spindles and other microtubule arrays.

The Betterton Lab studies the physics of cell division and related biophysics. They are specifically interested in motor protein dynamics and microtubule length regulation, cytoskeletal active matter, ...

E.R. Steuer, L. Wordeman, T.A. Schroer, M.P. Sheetz, "Localization of cytoplasmic dynein to mitotic spindles and kinetochores," Nature, 345:266-68, 1990. Michael Sheetz (Duke University Medical Center ...

In an article published in the journal PloS Computational Biology, the scientists focused on the length of the mitotic ...