Expression of cytokeratin and SMA has been shown in spontaneous and transgenic mouse mammary tumors and in human tumors of mammary origin 2. The immunohistochemical characteristics of a tissue ...

Huch’s pancreatic organoids are now a promising avenue for disease modeling and generating precision medicines to treat ...

Specific areas of interest are: The interplay of Wnt and Fgf family members in mammary gland development and breast cancer. Translational regulation as a new therapeutic vulnerability in triple ...

We strive to understand the molecular and cellular regulation of epithelial appendage (hair, mammary gland, tooth) development and how they are perturbed in diseases such as congenital disorders or ...

The Netherlands Cancer Institute has found that the estrous cycle stage significantly influences mammary tumors' sensitivity to chemotherapy. In mouse models of breast cancer, treatment initiated ...