Notably, this approach did not damage healthy early blood stem cells or immune cells in human and AML mouse models. When leukemia infiltrates the bone marrow, it generates CD38-positive abnormal ...

More information: Heejin Jun et al, CD13-targeting and TRAIL-displaying protein nanoparticles effectively induce apoptotic ...

Triplet Regimen Yields Promising Response in Advanced-Phase Chronic Myeloid Leukemia Sep. 17, 2024 — According to new research, 80% of patients with previously untreated or relapsed/refractory ...

In 1957, Kieler and his associates, 9 using various concentrations of nitrous oxide, nitrogen and oxygen on embryonic mouse-heart ... nitrous oxide in chronic myeloid leukemia.

We combine genetic mouse models and pre-clinical mouse models using patient samples to study genes involved in pediatric (acute lymphoblastic leukemia) and adult (chronic myeloid leukemia and acute ...

The team identified a specific population of immune cells that play a critical role in successful treatment of relapsed acute myeloid leukemia (AML). A research team from Columbia Engineering and ...

Kura and Kyowa used the announcement to confirm that they are on track to file a new drug approval application with the FDA ...