Stem cell biology; regeneration; skeletal muscle regeneration and aging; skeletal muscle stem cells and gene therapy; growth factors and signal transduction; mouse molecular genetics; muscular ...

Our research group is investigating the mechanisms that regulate skeletal muscle regeneration, focusing on skeletal muscle stem cells. We are interested in the biogenesis ... An additional interest is ...

From stem cell-recruiting gels to hormone cycle restoration, Tracy Criswell has big ideas about how to combat age-related decline in muscle regeneration. Hannah joined Drug Discovery News ... Wake ...

Impact of the stem cell niche on aging: we study the communication between stem cells and their niche (e.g. neighbor cells, ECM) in multiple tissues including the intestine, mammary, skeletal muscle, ...

However, despite early breakthroughs, progress in understanding the aging ... the blood stem cells of recipients compared with those of donors. Sustainable engraftment of heart muscle cells ...

In their study, "Transcriptomic Analysis of Skeletal Muscle Regeneration Across Mouse Lifespan Identifies Altered Stem Cell States," published in Nature Aging, researchers sampled cells from young ...

STEM cell patches can fix heart failure by regenerating the muscle, tests show. The treatment was found to increase the thickness of the heart wall, helping it to contract better to pump blood ...

Members of Theme Six are developing stem cell and cellular reprogramming ... of cardiac fibroblasts into cardiac muscle as a way to enhance heart function after ischemic injury. This novel method was ...

it rescued their regeneration capacity. 6 This isn’t to say that young and aged stem cells are exactly the same—they still have different epigenetic and transcriptional signatures—but at least in the ...

Maresin 1 repletion improves muscle regeneration after volumetric muscle loss ... Aguilar CA. Murine muscle stem cell response to perturbations of the neuromuscular junction are attenuated with aging.