Ulcer complications associated with the use of NSAIDs, in high-risk patients, are often caused by a failure to identify patients' risk factors, concomitant use of aspirin or multiple NSAIDs ...

Medically reviewed by Kumkum S. Patel, MD A peptic ulcer is the term used for a sore that occurs in the mucosal lining of the stomach, small intestine, or esophagus. When the ulcer is in the stomach ...

Nearly every arthritis sufferer has taken a traditional painkiller like aspirin or Aleve. They are a great solution for relieving pain and inflammation, but there's a definite downside.

All NSAIDs variably inhibit COX-1 and COX-2 and the mechanisms of inhibition fall into three broad categories, although there are exceptions. For example, nimesulide is a weak competitive ...