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21 天
Nanog 在软骨细胞分化中的关键作用及调控机制揭秘
为探究 Nanog 对软骨细胞的作用,研究人员发现其诱导软骨细胞去分化,且受 p53/KLF4 和 p38/AKT 通路调控。 同源盒蛋白 Nanog 是转录因子家族的成员,在维持胚胎干细胞(ESCs)的多能性和自我更新方面发挥着至关重要的作用。由于其功能多样,Nanog 在多种细胞类型 ...
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