It is, therefore, possible to hypothesize that an epithelial EPR effect exists in patients ... Aside from the role of nanoparticles in the local accumulation of drug load, drug penetration into ...

A novel encapsulated nanoparticle EPR imaging agent has been described which could be used in the future to bring EPR imaging for guidance of radiotherapy into clinical reality.

One way is through a passive targeting mechanism called the enhanced permeability and retention (EPR) effect. Compared to normal tissues, solid tumors have leaky vasculature, so small nanoparticles ...