Purpose: Late-infantile neuronal ceroid lipofuscinosis (LINCL), an autosomal recessively inherited lysosomal storage disorder characterized by autofluorescent inclusions and rapid progression of ...

The NCLs (neuronal ceroid lipofuscinosis) are pediatric neurodegenerative disorders. The nine clinical variants are caused by mutations in different genes (CLN1–CLN9). Six of the genes are ...

Batten disease is a rare genetic disorder affecting 3 in 100,000 babies in the U.S., causing neurodegeneration, seizures, ...

GRIEVING the loss of one child is devastating, but preparing to lose another is unimaginable. For single mother Zaitul Akma Muhd Zain, 39, this is her reality. Having lost her eight-year-old ...

Making memories is something most people do everyday, sometimes without realizing just how important memories can be.

NICE had been assessing Brineura (cerliponase alfa) for children with neuronal ceroid lipofuscinosis type 2 (CLN2), a rare inherited condition affecting between one and six babies each year in the UK.

Galvin, N., Vogler, C., Levy, B., Kovacs, A., Griffey, M., Sands, M.S. A murine model of infantile neuronal ceroid lipofuscinosis - Ultrastructural evaluation of ...