were triggered to form chromatin fibers known as neutrophil extracellular traps (NETs) that contained the target autoantigens proteinase 3 and myeloperoxidase. Although NETs had previously been ...

An imbalance of neutrophil elastase and its inhibitor, α 1-antitrypsin, and of matrix metalloprotease-9 and its inhibitor, tissue inhibitor of matrix metalloproteases 1 (TIMP-1), lead to severe ...

As it succumbs, the neutrophil releases its DNA, histones, and granule proteins, leaving behind a mesh-like structure, a net. E. coli and other bacteria become entrapped just as insects are snared ...