But the pathognomonic feature of osteitis deformans must be seen on histology ... porosity and subperiosteal new bone formation and contributes to the abnormal structural integrity.

These disorders stem from complex genetic and environmental interactions that disrupt bone formation and joint development ... provides compelling new evidence of LRP1's essential role in bone ...

These mutations disrupt the normal processes of bone formation and repair ... This research offers new hope for individuals with skeletal disorders caused by FGFR mutations.