Primarily, next-generation sequencing technologies operate through step-wise cycles of polymerase-based extension or oligonucleotide ligation that rely on piecing together short reads from fragmented ...

Next-generation DNA sequencing has started a revolution in ... One of the tricks to getting tSMS to work is in the next step in the process: the labeling dye is cleaved off, allowing incorporation ...

Long-read, single-molecule DNA sequencing is a foundational method in genomics research, with applications including identifying complex structural variants and analyzing whole chromosomes. However, ...

DNA sequencing is a powerful approach for decoding a number of human diseases, including cancers. The advent of next-generation sequencing (NGS) technologies has reduced sequencing cost by orders ...

One of UMass Lowell’s Core Research Facilities, the Next Generation Sequencing & Genomics Lab provides Next-Generation DNA & RNA sequencing services and technical expertise including NGS library prep, ...

The current library preparation methods for next-generation sequencing are time-consuming and prone to considerable sample loss. Even before library preparation, the recovered DNA must be purified ...

The Genomic and RNA Profiling core offers a one-stop WGBS workflow starting with DNA fragmentation, bisulfite conversion, library preparation and ending with sequencing. Nanpore sequencing is a ...

Explore a cfDNA library preparation workflow that provides high yield and conversion to improve sensitivity and detection of low variant allele frequencies (VAF). Cell-free DNA (cfDNA) contains ...

Unisa has launched Africa’s first next-generation DNA sequencing platform, the PacBio Revio, developed in collaboration with Inqaba Biotec. The first-of-its-kind breakthrough signifies a major ...