NSAIDs are the principal agents used for managing pain in patients with chronically painful diseases, such as osteoarthritis. However, the withdrawal of the selective cyclo-oxygenase 2 (COX2 ...

Conventional medical treatment for rheumatoid arthritis and osteoarthritis includes the use of NSAIDs (traditional and selective inhibitors of cyclooxygenase [COX]-2), because they provide ...

Rofecoxib and lumiracoxib were associated with the highest risk of MI (rate ratio: 2.12 and 2.00; 95% CI: 1.26–3.56 and 0.71–6.21, respectively); Ibuprofen and diclofenac were associated with ...