APG-777 is an anti-IL-13 humanized monoclonal antibody (mAb) designed to block Th2 inflammatory signaling mediated by the IL-13Rα1/IL-4Rα complex, while APG-990 is a fully human anti-OX40L mAb that ...

The problematic molecules—ICOSL, OX40L, and CD30L—keep memory T cells in the lungs on high alert. While typically these T cells are beneficial, preserving information about past infections to ...