Loss of normal p53 function has been associated with resistance to both chemotherapy and radiotherapy. Introduction of wild-type (wt) p53 by means of adenoviral vectors has been shown to inhibit ...

Scientists at Sanford Burnham Prebys and collaborators across the country published findings March 5, 2025, in Nature ...

In humans and other multicellular organisms, cells multiply. This defining feature allows embryos to grow into adulthood, and ...

Around this time, cancer researchers across different disciplines concluded that the gene encoding p53 was an oncogene. Once they started searching, scientists found p53 in almost every cancer type.

In humans and other multicellular organisms, cells multiply. This defining feature allows embryos to grow into adulthood, and enables the healing of the many bumps, bruises and scrapes along the way.

A first-ever analysis of the whole Greenland shark genome gives researchers a couple of clues to their longevity.

The stem cell signal Msi2 plays a dual role in lung cancer, acting as a signal that is not only essential for initiation, but also for propagation of the tumor.

A team from University Hospitals Seidman Cancer Center is launching the nation's first-ever clinical trials evaluating the ...