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发现司来吉兰新神经保护机制:抑制蛋白质二硫键异构酶促凋亡活性
在这项研究中,研究人员运用了多种先进的技术方法。其中,活性蛋白质谱分析(ABPP)技术,就像是一个精准的 “分子探测器”,利用司来吉兰独特的 N - 炔丙基胺部分进行点击化学,帮助研究人员筛选并识别出司来吉兰在小鼠多巴胺能神经元 MN9D ...
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