实验验证阶段，通过 RT-qPCR 检测发现，K1 抗体能显著富集内源性逆转录病毒（ERV）、部分 SINE 和长散在核元件（LINE）等来源的 dsRNA；同时，通过蛋白质免疫印迹分析证实，已知的 dsRBPs 如 ADAR1、PKR 和 STAU1 等，在 K1 共沉淀洗脱液中高度富集。大规模实验中 ...

为解决小麦赤霉病（FHB）防治难题，研究人员探索纳米技术与 SIGS-dsRNA 技术，发现该技术可有效防控病害，意义重大。 ### 小麦赤霉病防治的新曙光：纳米技术与 SIGS-dsRNA 技术的奇妙结合 在全球粮食生产的大舞台上，小麦是当之无愧的主角之一，它为数十亿人 ...

Double-stranded RNA (dsRNA)–dependent protein kinase PKR is a growth inhibitory protein that induces death in virally infected cells, but its potential in controlling tumor growth is unknown. In ...

In many species, introduction of double-stranded RNA (dsRNA) induces potent and specific gene silencing, a phenomenon called RNA interference or RNAi. The apparently widespread nature of RNAi in ...

RNA-based medicines are one of the most promising ways to fight human disease, as demonstrated by the recent successes of RNA vaccines and double-stranded RNA (dsRNA) therapies. But while health ...