这项技术突破不仅填补了PTEN动态监测的世纪空白,更开启了在体分子成像的新纪元。 在微观的细胞宇宙中,一个名为PTEN(Phosphatase and tensin homolog ...
研究人员们巧妙地利用荧光共振能量转移原理,将PTEN蛋白改造为构象敏感的"分子探针"。通过在其N端和C端分别标记绿色荧光蛋白与淬灭蛋白 ...
在微观的细胞宇宙中,一个名为PTEN(Phosphatase and tensin homolog)的蛋白质如同精密的分子刹车,时刻调控着细胞增殖与存亡。这个仅有403个氨基酸的 ...
MD-PhD student Tomer Kagan and Dr. Tal Laviv. A novel scientific method developed at Tel Aviv University promises to ...
为探究腭裂(CP)发病机制,研究人员构建 Pten 敲低模型,发现阻断 Pten 可缓解 CP,为防治提供新方向。 腭裂,这个在胚胎发育过程中悄然出现的 “小恶魔”,严重影响着无数患儿的生活。它是一种常见的先天性颅面畸形,像一道鸿沟横亘在口腔的软硬组织之间。
Get Instant Summarized Text (Gist) A new method has been developed to enhance the study of the PTEN gene, crucial for regulating cellular growth and linked to conditions like cancer and autism ...
Many genes are involved in this regulation, but one gene in particular—PTEN (Phosphatase and Tensin Homologue)—plays a central role. Mutations in PTEN are linked to a variety of conditions ...
Conclusion: The overall diagnostic yield was 10% (7/71). PTEN gene sequencing should be considered in any child with macrocephaly and autism or developmental delay. Metabolic screening may not be ...