Microscope image of mouse pancreatic tissue, with insulin-producing tissue marked in brown. Early-life exposure to a specific gut microbe appears to boost growth of insulin-producing tissue, the new ...

Fluorescent microscope image of a mouse pancreatic islet, the part of the pancreas that makes insulin. Green marks cells that are multiplying. Pancreatic cells don’t generally grow in adulthood, but ...

The pancreatic islet is the only human tissue that produces insulin in response to rising blood glucose levels. In type 1 diabetes, the immune system attacks and slowly destroys these islets ...

The microbiome shapes the development of insulin-producing cells in infancy, leading to long-term changes in metabolism and ...

More information: Rebecca Craig-Schapiro et al, Single-cell atlas of human pancreatic islet and acinar endothelial cells in health and diabetes, Nature Communications (2025). DOI: 10.1038/s41467 ...

Type 1 diabetes – which affects around nine million people globally – occurs when the body’s immune system destroys insulin-producing islet cells in the pancreas. Islet transplantation has long been ...

A recent study published in Diabetologia has identified insulinoma-associated protein 2 autoantibody (IA-2A) positivity as a ...

The results could ultimately help doctors reduce the risk of type 1 diabetes—or potentially even restore lost metabolic function in adulthood—by providing gut microbes that help the pancreas grow and ...

What Are Pancreatic Neuroendocrine Tumors (NETs)? It's natural to feel a little overwhelmed when you get news that you have a pancreatic neuroendocrine tumor (NET). If you're like most folks ...

Risk for pancreatitis was not elevated among users of tirzepatide relative to placebo, despite the presence of elevated pancreatic enzymes.