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Pbx3调控 I 型干扰素反应基因在 MLL-AF9 诱导的 AML 进展中的关键作用及 ...
为探究 AML 进展中细胞内炎症状态变化,研究人员构建小鼠 AML 模型,发现 Pbx 3 影响疾病进展,I 型干扰素或可治疗。 细胞内在的炎症信号抑制有助于急性髓系白血病(AML)原始细胞的存活。然而,在 AML 进展过程中,细胞内在的炎症状态如何变化仍不清楚。在 ...
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