This phenomenon is termed peripheral sensitization. Following nerve damage, as a consequence of the peripheral sensitization, second order nociceptive neurons develop an increased background ...

(rPMS) on pain perception in an experimental pain model and concluded that the analgesic properties of rPMS could be largely attributed to its auditory component rather than peripheral nerve ...

2 A drug that induces peripheral sensitization of somatic or sympathetic nerves and/or central sensitization of brain systems could potentiate the pathophysiological mechanisms that contribute to ...

It is postulated that cytokines/chemokines sustain neuro-inflammation and neuropathic pain by acting on sensory cells such as Schwann cells in DRG neurons resulting in peripheral sensitization. These ...