The action of thrombin on fibrinogen is not responsible for its effect on platelets. Thrombin does, however, have an enzyme effect on a platelet constituent: this requires an unsubstituted serine ...

Platelet substitutes are a new class of artificial ... Washington, DC, U.S. General Accounting Office (1997). Levi, M. et al. Fibrinogen–coated albumin microcapsules reduce bleeding in severely ...