DNA replication and recombination ... Fien, K. et al. 2004. Primer utilization by DNA polymerase alpha-primase is influenced by its interaction with Mcm10p. The Journal of Biological Chemistry ...

During circular DNA replication, the excised primer is readily replaced by nucleotides, leaving no gap in the newly synthesized DNA. In contrast, in linear DNA replication, there is always a small ...

Remarkably, bypass only occurred when the Pol III HE was integrated in the replisome. The enzyme itself could not bypass template damage in a primer-extension assay. These findings suggest that DNA ...

Original DNA template - DNA is a double helix made of two complementary strands. Each strand can be used as a template to create a new DNA molecule. Free DNA nucleotides – needed to form the new ...

the helix structure is unwound special molecules break the weak hydrogen bonds between bases, which are holding the two strands together this process occurs at several locations on a DNA molecule ...