If this occurs, additional protease inhibitors can be added to the TGMC(0.1) buffer. Problem: An anticipated interaction is not observed. Solution: The amount of bait protein immobilized on the ...

All biological function is dependent on how different proteins interact with each other. Protein-protein interactions ...

Successful research in targeted protein degradation depends not only on measurements at high sensitivity, speed and precision ...

Ali receives this award for his work on genetically-encoded cyclic peptide libraries and their use for identifying inhibitors of a variety of protein-protein interactions. Ali’s work has resulted in ...

Discover how next-generation kinase inhibitors are transforming clinical therapy byovercoming resistance and enhancing ...

Researchers at Children’s Hospital of Fudan University, Shanghaitech University and Suzhou Zhongke New Drug Incubator Biomedical Technology Co. Ltd. have identified WD repeat-containing protein 5 ...

Researchers have made a significant breakthrough in cancer drug discovery by identifying a new binding site on the eukaryotic initiation factor 4 ...