Some pyrimidine derivatives, such as pyrithiobac and bispyribac, are used as herbicides to control weeds in agricultural settings. These compounds inhibit the enzyme acetolactate synthase (ALS), which ...
This image illustrates the chemical structure of a purine molecule, highlighting the numbering of the carbon and nitrogen atoms. The purine structure consists of a pyrimidine ring (positions 1 to 6) ...
covers a polymorph of the non-steroidal anti-inflammatory molecule which inhibits dihydroorotate dehydrogenase (DHODH), a key enzyme involved in the pyrimidine synthesis pathway. This development ...
The phosphate groups are closely packed about the axis of the molecule, with the pentose residues surrounding them, and the purine and pyrimidine groups projecting radially, their planes being ...
During photoreactivation, an enzyme called photolyase binds pyrimidine dimer lesions; in addition, a second molecule known as chromophore converts light energy into the chemical energy required to ...