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多组学解析精神障碍相关遗传通路在炎症性肠病发病机制中的作用
研究人员探索精神障碍相关基因与 IBD 风险关联,发现 QDPR、DBI、MAX 和 HP 基因,为疾病干预提供新靶点。 炎症性肠病(IBD)是一种主要影响胃肠道的慢性系统性炎症性疾病,包括克罗恩病(Crohn’s disease)和溃疡性结肠炎(ulcerative colitis,UC)两种临床亚型。
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