A NEWLY synthesized compound, propranolol, was found to be a very potent, β-receptor adrenergic blocking agent 1. Since the drug blocks the vasodilator (β-receptor stimulating) effects of ...

Crowther, A. F., and Smith, L. H., U.K. Patent No. 994,918. Howe, R., I.C.I. Ltd., Pharmaceuticals Division (unpublished work). Bond, P. A., McLoughlin, B. J., and ...