为探究 FDX 1 在透明细胞肾细胞癌（ccRCC）中的作用，研究人员经多实验分析，发现其可抑制 ccRCC 生长转移，为治疗提供新靶点。

肾细胞癌（Renal Cell Carcinoma，RCC）占肾癌的 85%，主要包含透明细胞肾细胞癌（clear cell RCC，ccRCC，80%）、乳头状肾细胞癌（papillary RCC，pRCC，15%）和嫌色细胞肾细胞癌（chromophobe RCC，chRCC，5%）这三种亚型。 ccRCC 最为常见且侵袭性强，约 20 - 40% 的患者在根治性治疗 ...

Burchfield, MD, and other participants discussed their experiences with the frontline combination regimens for advanced renal ...

empowering genes that promote tumor growth in ccRCC, the most common type of kidney cancer. 2 Casdatifan binds to HIF2⍺, disabling these mechanisms to cause cancer cell death. RCC is associated ...

Clear cell RCC (ccRCC) is almost universally associated with HIF-2a dysregulation. Casdatifan is currently being evaluated in ARC-20, a Phase 1/1b study in renal cell carcinoma and other cancers.

PSMA may be a noninvasive biomarker for predicting treatment response in metastatic clear cell renal cell carcinoma (RCC).

saying "there remains a high unmet clinical need to improve outcomes after surgery for patients with high-risk RCC". Dr Braun said: “For patients with high-risk ccRCC, we want to improve post ...

The trial marks a significant milestone for Inceptor Bio's efforts to address the unmet medical needs of patients with clear cell Renal Cell Carcinoma (ccRCC) IB-T101 is an autologous CD70 CAR-T ...

Results from the COBALT-RCC study were presented by Samer Srour ... a tumor antigen present at high levels in ccRCC. CD70 is known to have a role in the suppressive immune tumor microenvironment ...