One of the most remarkable features of rRNA is its catalytic activity. The large subunit rRNA, in particular, is responsible for the peptidyl transferase reaction, which catalyzes the formation of ...

Some RNA molecules, called ribozymes, possess catalytic activity and can catalyze chemical reactions. For example, the ribosome itself is a ribozyme, as the rRNA component catalyzes the formation of ...

RNA molecules are an integral part of the human body: In cells, they ensure the transfer of genetic information and regulate the activity of ... that lost their catalytic function during evolution ...

This mutation abolishes the enzyme's catalytic activity while retaining its interaction with RNA polymerase II. By generating a Setd2-CD knockin mouse model, the researchers compared it with a ...

suggesting that the catalytic activity of Setd2 is crucial for these developmental processes. RNA sequencing and single-cell RNA sequencing analyses of the yolk sac and embryos revealed ...

I am interested in the chemistry and biochemistry of DNA and RNA, with special regard to novel structural and functional properties for these nucleic acids. Two major areas of interest are: New ...

RNA molecules are an integral part of the human body: In cells, they ensure the transfer of genetic information and regulate the activity of ... that lost their catalytic function during evolution ...

RNA molecules are an integral part of the ... More information: Hsuan-Ai Chen et al, Structure and catalytic activity of the SAM-utilizing ribozyme SAMURI, Nature Chemical Biology (2025).