破骨细胞活化上，WT + DMM 组术后 4 周破骨细胞数量显著增加，THM + DMM 组术后 1 周就显著增加，且两组中 RANKL 阳性骨细胞百分比均随时间上升。骨细胞和空骨陷窝数量方面，WT + DMM 组术后骨细胞数量减少、空骨陷窝数量增加，4 周时与假手术组差异显著；THM + DMM ...

为探究硅酸三钙（Bio C Temp）和氢氧化钙（Calcicur）基根管内封药对无症状根尖周病变中核因子 κB 受体活化因子配体（RANKL）、骨保护素（OPG）等炎症介质释放的影响，研究人员开展相关研究。结果显示两种封药均有效降低炎症介质水平，氢氧化钙组降低幅度更大 ...

No writing assistance was utilized in the production of this manuscript. RANKL expression is stimulated in osteoblasts and osteocytes by cytokines and hormones, and plays an important role in ...

Chondroitin sulfate and the combination therapy reduced the expression of RANKL in patients not receiving vitamin D, but in those taking vitamin D, the effect failed to reach significance.

Prolia works differently from Evenity by binding to a different protein called RANK ligand (RANKL). RANKL is essential for the formation, function, and survival of the primary cells responsible ...