So, compounds that modulate the epigenetic regulation of gene expression, such as HDAC inhibitors, might have antidepressant actions. Nestler and colleagues used a mouse model of chronic social ...

Imprinting is yet another process involved in eukaryotic gene regulation; this process involves the silencing of one of the two alleles of a gene for a cell's entire life span. Imprinting affects ...

Fred Hutch researchers have done pioneering work in the areas of gene regulation, chromatin organization and cell cycle state, including quiescence. Gene expression is important because a specific ...

These two mechanisms seemed to function separately, each playing its own role in distinct stages of the gene regulation process. Perhaps that was a mistake. In a publication in the journal Cell ...

When gene regulation fails, or specific genes are ... or convert genetic information into protein products that carry out actions specified in the DNA code. Scientists have long studied the ...

In addition, the use of tools like lentiMPRA and MPRALegNet will help to better equip researchers to unravel the complexities of gene regulation and to explore the vast, uncharted territories of ...

Understanding the language of gene regulation holds the potential for great benefit to human health, said Yang E. Li, assistant professor in the departments of neurosurgery and genetics at ...

Along our journey, we shall reveal basic principles of gene regulation. We aim to exploit the new knowledge to help devise novel treatments of many diseases that stem from misregulated gene ...

A research team at KAIST has identified the core gene expression networks regulated ... the precise mechanism of its action was unclear. SRF is a transcription factor directly controlling the ...

A research team at KAIST has identified the core gene expression networks regulated ... the precise mechanism of its action was unclear. SRF is a transcription factor directly controlling the ...