CO), which measures activated Rho-GTP, per the manufacturer's instructions. Results are expressed as mean ± SE. Analysis of variance (for LIVE/DEAD) and t tests (all other experiments ...

In this GTP-bound, active, state ... Other members of the Ras superfamily, such as Rho, Rab and Ran proteins, are regulated by similar interactions with nucleotides. However, they interact ...

Rho GTPases are molecular switches that switch between an active and an inactive state by binding to the phosphate compounds GTP and GDP. GTP corresponds to the 'on' position of the switch and ...