This nationwide study highlights the prevalent use of oral glucocorticoids in French patients with SLE and shows that ...

长期以来，尽管遗传因素在SLE的发病中的重要作用已是共识，但其确切作用始终未得到揭示。近年来，数个遗传学研究表明单基因突变即可导致SLE，单基因狼疮的概念呼之欲出。然而临床上数量庞大的SLE患者得到明确遗传学解释的仍然是少数，这提示SLE发病的遗传基 ...

Researchers identify a new player in human immunity that can go rogue and turn the immune system against the body’s own ...

Autoimmune diseases, such as rheumatoid arthritis, systemic lupus erythematosus and Sjögren’s syndrome, are caused by antibodies and immune cells damaging host tissues, and can elicit a wide ...

Conduit Pharmaceuticals and Charles River Laboratories have announced a partnership to evaluate AZD1656, a glucokinase activator, in a preclinical model of systemic lupus erythematosus (SLE).

Cabaletta’s new data slice for its investigational CD19-CAR T cell therapy shows “robust benefit” for patients with lupus and ...

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Incurable Autoimmune Disease Systemic Lupus Erythematosus (SLE): New Genetic Findings Open Up Perspectives for Future Therapeutic Approaches Jan. 14, 2024 — Systemic lupus erythematosus (SLE ...

Before taking its repurposed diabetes drug candidate into a phase 2 lupus trial, Conduit Pharmaceuticals is tapping Charles ...