Numerous motor and structural proteins compose a highly ordered structure known as the sarcomere, the basic unit of muscle contraction in heart and skeletal muscles. Sarcomeric myosin heavy chain ...

An individual sarcomere contains ... helped us learn how muscles can change their shapes to produce movements. Clark, M. Milestone 3 (1954): Sliding filament model for muscle contraction.

Three-filament model of the sarcomere and domain architecture of titin isoforms according to Freiburg ... Cardiac muscle co-expresses N2B and N2BA isoforms, skeletal muscle has N2A isoform only.