A novel reporter protein has been developed to enable the investigation of protein biogenesis in the ER and its disruption in disease.

Often presented together with obesity, insulin resistance and type 2 diabetes, these chronic diseases are strongly influenced by pathways ... in the study of endoplasmic reticulum stress as ...

A newly developed luciferase-based reporter can detect problems in protein translocation and disulfide bond formation in the ...

Protein synthesis in eukaryotic cells--found in plants, animals, and fungi--involves more than just the straightforward ...

The translocation of secretory proteins across intracellular ... directs the ribosome to the rough endoplasmic reticulum (ER) membrane and initiates the transport of the growing peptide chain ...

Protein synthesis in eukaryotic cells found in plants, animals, and fungi involves more than just the straightforward ...

Nearly one-third of all human proteins must be transported to the endoplasmic reticulum (ER ... block the biosynthesis of harmful secretory pathway proteins,” highlights Kadokura.

A newly developed luciferase-based reporter can detect problems in protein translocation and disulfide bond formation in the endoplasmic reticulum (ER). Inspired by natural mechanisms found in ...