Spir proteins nucleate actin polymerization by assembling a linear actin oligomer along a cluster of four actin-binding WH2 domains, and this process is enhanced by formins of the Cappuccino family.

In all eukaryotic cells, actin proteins come together to form a network of thin filaments that spread throughout the cell. These filaments play a role in the cell’s structure and movement, its ...

Actin proteins group together to form a network of thin filaments that spread throughout eukaryotic cells. These filaments are involved in giving the cell its structure, allowing the cell to move, and ...