Signal transduction describes the process of conversion of external signals, such as hormones, growth factors, neurotransmitters, and cytokines, to a specific internal cellular response ...

If there is one thing that is known about the mechanisms that govern signal transduction, it's that not very much is known. When signaling molecules bind to a cellular receptor, they set off a chain ...

A new funding initiative from the National Natural Science Foundation of China provides a model of a targeted funding program in the area of signal transduction. Chemical biology has been ...

这项名为“仑伐替尼联合吉非替尼在仑伐替尼耐药的肝细胞癌患者中的疗效与安全性：前瞻性单臂探索性试验”的研究，显示出令人鼓舞的结果。在EGFR高表达以及耐药的肝细胞癌患者中，采用这种双靶向治疗的客观缓解率（ORR）达到30.0%，而疾病控制率（DCR）更是高达76.7%。据改良实体瘤疗效标准（mRECIST），中位无进展生存期（PFS）为4.4个月，总生存期（OS）同时为13.7个月。

DIRECT EFFECTS: Steven Hebert, left, and Edward Brown and colleagues found that Ca 2+ receptors influence signal transduction. "Although the importance of intracellular Ca2+ ions in signal ...

A research team led by Dr. Tetsuya Muramoto from the Faculty of Science at Toho University has demonstrated the mechanisms by which periodic chemical signal frequencies in cells regulate gene ...

The findings highlight the significance of frequency-selective cellular responses in developmental biology, providing valuable insights into the intercellular signal transduction mechanisms.

Researchers from the University of Illinois have discovered a key factor responsible for facilitating signal transduction in Cys-loop receptors, providing insight into a longstanding question in ...

Z526- a novel dithiocarbamate-like compound reverses cancer associated cachexia via mitigating NF-B signaling and oxidative ...