Infertility is a major global challenge associated with physiological and psychological impact. Genetic mutations that affect ...

The pair had helped identify a still-unnamed disease, which they had tied to a particular gene and to a particular somatic mutation—a genetic change that had not been passed down from a parent and was ...

Sperm cell adaptations include ... change in the structure of a gene or in the number of chromosomes in a cell. Mutations can occur naturally before a cell divides. They can also be caused ...

A potential undesirable side effect of somatic gene therapy is that, during gene delivery, foreign DNA reaches the gonadal tissue and inserts into the germ cell genome, with the risk of ...

The result is a state called “somatic mosaicism,” in which two or more groups of cells in the same body possess different genetic compositions. In recent years, the discovery of conditions such as ...

Every biology student learns that each cell in our body (except sperm and eggs) contains two copies of each gene ... The new ...

Researchers at Columbia University reveal how monoallelic expression (MAE) shapes genetic disease outcomes. By favoring one ...

Loss of the Y chromosome (LOY) in men, a dynamic mutation linked to aging, impairs immune function and increases risks of ...

New research reveals that certain cells inactivate one parent’s copy of a gene, leading to a bias in gene activity that may ...

Both deletion mutations and aberrant expression of mtDNA ... as they are not passed on by sperm cells to the baby. Each one of us shares mtDNA with only a subset of our maternal relatives, for ...