The submucosal layer consists of a highly cellular stroma of spindle cells with elongated nuclei similar to the “ovarian stroma” which is a key pathologic feature distinguishing these lesions.

Spindle fibers form a protein structure that divides the genetic material in a cell. The spindle is necessary to equally divide the chromosomes in a parental cell into two daughter cells during ...

Many cells were swollen and disorganized. In the dermis, epithelioid and spindle-shaped tumor cells, demarcated by thin fibrous trabeculae, were arranged in interweaving bundles. Due to the ...

In the Phase II ADVL1823 study, researchers evaluated Vitrakvi in children with newly diagnosed IFS and other solid tumors with NTRK fusions.