在开始研究之前，研究人员已经知道Syngap1基因能够实现触觉感知。在2018年发表于《Nature Neuroscience》的一项研究中，Rumbaugh实验室记录了携带该基因突变副本的儿童家庭的经历。这些儿童对触觉的反应不正常，通常对疼痛的耐受性异常高。在一个案例中，一个孩子忽视了自己折断的手指，持续了四天。

Dr. Julia Dallman, Associate Professor of Biology at the University of Miami, alongside her research team, received a $65,000 grant from the SynGAP Research Fund (SRF). This funding supports their ...

Research from The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology shows a gene called Syngap1 ...

The SYNGAP1 gene, which supports the production of a protein called SynGAP (Synaptic Ras GTPase-Activating Protein), is known to play a key role in supporting the development of synapses and ...

Helen and Craig Woodier, the parents of Toby, 11, have been fighting for years to get treatment for their son who is ...

The SYNGAP1 gene is crucial for cognitive function, as it supports synapse development and neural circuit formation. Mutations in this gene are linked to learning disabilities, autism, and epilepsy.

Usually, it's effortless. Research from The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology shows that a gene called Syngap1 enables touch-based perception ...

Mill Valley, CA – February 11, 2025 – The SynGAP Research Fund 501(c)(3) dba Cure SYNGAP1 proudly announces the release of its inaugural Impact Report, a transparent and celebratory reporting ...

Stoke's broader pipeline, including treatments for SYNGAP1-related disorders, Rett syndrome, and Autosomal Dominant Optic Atrophy, could expand its market potential if RNA modulation proves ...

Toby Woodier, currently 11, was diagnosed with the rare genetic disorder Syngap1 at the age of nine and is unable to speak. His parents, Helen, 48, and Craig Woodier, 51, are now seeking ...