Monocytes are a type of immune cell never reported to play a role in T cell stimulation," explains Elewaut. For the longest time, researchers had been looking at dendritic cells as the main ...

Regulatory T ... target cell to two potently inhibitory molecules. Suppression by modulation of DC maturation or function: two mechanisms have been proposed. First, cytotoxic T-lymphocyte antigen ...

New findings reveal how cancer manipulates immune pathways and highlight therapeutic strategies to unleash T-cells against even the most resistant tumors. Study: Cancer cells impair monocyte ...

Regulatory T cells (TReg cells) are a special subset ... and skin injury, with monocytes/macrophages and interleukin-10 playing a key mechanistic role in the process.

The eyes have long been regarded as "immune-privileged" organs. Immunological system of ocular tissues prevents or resolves ...

are selected as a T cell lineage distinct from conventional cytotoxic T lymphocytes (CTLs). We were also the first to report that tumor growth induces monocyte-derived tumor-associated macrophages ...

Initial clinical observations suggest high level of T cells reprogramming and CAR-T expansion at the starting dose without lymphodepletion At 28 ...