这篇综述对 11 项涉及 1573 名 1 型糖尿病（T1D）患者的试验进行分析，发现抗 CD3 单克隆抗体（mAb）能有效保护 C 肽分泌、减少胰岛素需求。年龄≤18 岁、诊断后≤6 周开始治疗、累积剂量≥25mg 时效果更好，但要注意平衡疗效和不良事件风险。 ### 1 型糖尿病（T1D ...

研究人员开展 1 型糖尿病（T1D）相关基因多态性研究，发现 ABCC8-3C>T 和 ENSA C>T 与 T1D 相关，意义重大。 1 型糖尿病（T1D）是一种多基因疾病，由胰岛素缺乏导致高血糖，涉及多种遗传和环境因素。KATP 通道由 KCNJ11 和 ABCC8 基因编码，ENSA 是一种内源性配体 ...

The aetiology of T1D is largely unknown, but it is thought that a genetic predisposition, environmental factors and distinctive metabolic changes are involved in the initiation, development and ...

The University of Bristol's Diabetes and Metabolism Research Group is conducting the T1D-DAB study to explore how age and ethnicity affect the development of Type 1 Diabetes. We know a lot about Type ...

The diagnosis of celiac disease in patients with T1D is challenging due to the common asymptomatic or oligosymptomatic presentation and fluctuating antibody levels. Researchers conducted this ...

The prevalence of cerebral small vessel disease (CSVD) nearly doubled over 7.5 years in neurologically asymptomatic patients with type 1 diabetes (T1D). The progression of cerebral microbleeds ...

The findings are particularly relevant as the T1D market continues to evolve. (Image Credits: Pexel) A new study has revealed that off-label use of semaglutide (Ozempic) and tirzepatide (Mounjaro ...

For P. D. Hinduja Hospital, Type 1 Diabetes (T1D) is a change-of-pace in care—beyond treatment and filled with hope and achievement, allowing resilience to grow. Ajay Hinduja, son of Prakash ...