资讯

腾讯网16 天
CRM：复旦大学附属肿瘤医院团队，发现LTA4H改善肿瘤微环境，并抑制 ...
抗TGF-β抗体和抗PD-1抗体联合治疗可显著改善LTA4H缺失HCC的免疫治疗耐药性。 研究发表在Cell Reports Medicine杂志上。 研究人员首先分析了LTA4H在人HCC组织 ...
腾讯网1 个月
Cell子刊：王红阳院士团队发现肝癌的新型防护因子——LTA4H
该研究表明，LTA4H 通过靶向 HNRNPA1/LTBP1/TGF-β 信号轴，改善肿瘤微环境并阻止肝细胞癌（HCC）进展。 了解肿瘤微环境（TME）内的免疫逃逸机制对于 ...
Medscape1 个月
Hepatocarcinogenesis: Is There Chemopreventive Potential for a COX-2 Inhibitor?
The mechanism mediating the reduced expression of COX-2, as well as of TGF-alpha and VEGF, in moderately differentiated HCC and poorly differentiated HCC remains unclear. It appears that these ...