12月30日，哈尔滨医科大学研究团队在期刊《Advanced Science》上发表了研究论文，题为“TRIM21 Promotes Tumor Growth and Gemcitabine Resistance in Pancreatic Cancer by ...

确定关键驱动因素和治疗靶点具有重要的临床价值。 12月30日，哈尔滨医科大学研究团队在期刊《Advanced Science》上发表了研究论文，题为“TRIM21 Promotes Tumor Growth and Gemcitabine Resistance in Pancreatic Cancer by Inhibiting EPHX1-Mediated Arachidonic Acid ...

James’ lab observed that antibodies can remain bound to adenovirus as it infects cells. The result sparked their curiosity, because they had previously shown that the intracellular protein TRIM21 ...

The team found that TTCM2 utilizes a naturally occurring protein in cells known as TRIM21, which functions as an intracellular antibody receptor – helping to mark the antibody-bound tau aggregates.

Objectives This study was aimed to assess whether QTc interval prolongation is associated with the presence of anti-Ro antibodies in SLE, particularly with reactivities against Ro52/TRIM21 antigens.

TRIM21 is particularly suited to this because ... symptoms slowed and they showed significantly better motor function, as assessed by an AI program that scored how well they ran.