Rapa’s approach yields a T cell product with a phenotype with anti-cancer effects, including: promotion of Th1/Tc1 cytokine secretion while eliminating regulatory T cells; elimination of ...

The proper functioning of the Th1 mediated immune response is necessary for the host’s ability to fight off intracellular infections and cancer. The lack of an effective Th1 immune response results in ...

Th1 cells can mount an anti-cancer response but are short-lived, while Th17 cells have greater longevity but are unable to mount a response. Combining the two harnesses the strengths of both ...

The researchers discovered that CD4 + Th1 cells, a type of immune cell, play a key role in targeting and eliminating dormant cancer cells. These cells, which can remain hidden in the body, have ...