这篇综述聚焦葡萄膜炎中 Th17 细胞，探讨其在炎症和免疫调节中的双重作用及治疗策略。 ### 引言 在免疫介导的疾病领域，Th17 细胞作为白细胞介素 - 17（IL-17）产生的 CD4 + T 辅助细胞，因其独特的功能和复杂的调控机制备受关注。它由具有不同调节方式和功能的 ...

本文通过多组学研究揭示 IRF4 在 Th17 和 iTreg 细胞中的调控机制，为免疫研究提供重要资源。 一、研究背景 转录因子干扰素调节因子 4（IRF4）是哺乳动物干扰素调节因子家族的九个成员之一，在先天和适应性免疫反应中发挥着关键作用。IRF4 的表达局限于免疫 ...

A research team has made further progress in the treatment of intestinal inflammation. A study shows that the semi-synthetic bile acid NorUDCA inhibits in the intestine the formation of ...

Background GPR171 suppresses T cell immune responses involved in antitumour immunity, while its role in inflammatory bowel disease (IBD) pathogenesis remains unclear. Objective We aimed to investigate ...

The study led by teams at The University of Manchester and National Institutes of Health in the USA, revealed that a specific type of immune cell, the Th17 cell, can be stimulated when you chew. The ...

In a nutshell Scientists discovered that an enzyme called SSAT1 turns helpful immune cells into harmful ones in psoriasis, ...

A research team from the Medical University of Vienna has made further progress in the treatment of intestinal inflammation.

MS Australia has recognised the work of University of Adelaide's Dr Iain Comerford with a $25,000 Incubator Grant.Dr Comerford, of the School of ...