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肌肉中的“弹性开关”:脯氨酸异构化与二硫键如何调控Titin蛋白的 ...
本研究聚焦Titin蛋白Ig结构域的力学稳定性调控机制,通过单分子磁镊技术揭示了脯氨酸异构化(Proline Isomerization)和二硫键(Disulfide Bond)对Titin Ig结构域力学性质的精细调控,为理解肌肉力学稳态提供了重要见解。 在肌肉的微观世界中,有一种名为Titin的巨型 ...
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