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生物通
17 天
TOLLIP 凝聚体:调控先天抗病毒免疫的新关键
为探究 MAVS 激活调控机制,研究人员发现 TOLLIP 凝聚体经 SENP1 促进 MAVS 去 SUMO 化,抑制先天抗病毒免疫。 在生命的微观战场上,免疫系统时刻都在与入侵的病原体进行着激烈战斗。其中,先天免疫系统作为抵御病原体的首道防线,发挥着至关重要的作用。
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